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the overexpression of FN14 is associated with the activation of the epidermal growth factor receptor (EGFR)
Species Human Accession Q96RG2 Amino Acid Sequence S949-S1323
its expression is tightly regulated (peaking 24–72 h post-activation and restrained by PD-1/CTLA-4 pathways) and its therapeutic agonism is exploited in immuno-oncology to overcome tumor-induced exhaustion
including MAPK1/ERK2 and/or MAPK3/ERK1
LILRB4 Recombinant Rabbit mAb (S-2504-22) Other Cytokines the overexpression of FN14 isProduct Specification Host Rabbit Antigen LILRB4 Synonyms Leukocyte immunoglobulin like receptor subfamily B member 4; B4; CD85 antigen like family member K; Immunoglobulin like transcript 3 (ILT 3); Leukocyte immunoglobulin like receptor 5 (LIR 5); Monocyte inhibitory receptor HM18; CD85k; ILT3; LIR5 Immunogen Recombinant Protein Location Cell membrane Accession Q8NHJ6 Clone Number S 2504 22 Antibody Type Recombinant mAb Isotype IgG Application WB,
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